The main objective of the present research study is to develop and validate a sensitive, specific, accurate and precise LC-MS method for the determination of p-Chloroaniline and (S)-5-Chloro-α-(cyclopropylethynyl)-2- amino-α- (trifluoromethyl) benzene methanol in Efavirenz bulk f...
Open access
Research Article10.9734/jpri/2021/v33i45B32818
A simple, accurate, precise method was developed for the simultaneous estimation of the Ertugliflozin and Sitagliptin in bulk and tablet dosage form. Chromatogram was run through Std Discovery C18150 x 4.6 mm, 5m. Mobile phase containing Buffer 0.1% OPA (2.2ph): Acetonitrile take...
Open access
Research Article10.9734/jpri/2022/v34i20B35829
Rivea ornata used traditionally for various disease of heart. However, its protective effect against oxidative stress induced injury is unclear and unproved. So, we attempted to investigate the protective role of butanol fraction of Rivea ornata on H9c2 cardiomyocytes against oxi...
Open access
Research Article10.9734/jpri/2021/v33i29A31569
Aim: Guggul lipid, a lipophillic antihyperlipidemic moiety, undergoes extensive first-pass metabolism and has low bioavailability. In order to address this limitation, guggul lipid loaded chitosan nanoparticles (GNPs) were designed, optimized and processed by 3- factor 3- level B...
Open access
Research Article10.9734/jpri/2021/v33i1831316
Aim: For the Method development and validation of Anabasine and Nornicotine in human plasma LC-MS/MS technique is used. Methodology: Operated in positive electron spray ionization which removes the hardness in ions. Metoprolol is used as an internal standard. Mass analyzers are u...
Open access
Research Article10.9734/jpri/2021/v33i1731301
Aim: To assess the drug-related problems (DRPs) and World Health Organization (WHO) core prescribing indicators among hospitalized diabetic patients. Methodology: A prospective, observational study was made among the diabetic inpatients of the General Medicine Department of a ter...
Open access
Research Article10.9734/jpri/2021/v33i531177
Aims: The present study was undertaken to examine the effect of patient education and counseling by pharmacist on quality of life and medication adherence on patients living with HIV/AIDS in rural settings. Study Design: It is a single group (without control group) pre- post inte...
Open access
Research Article10.9734/BJPR/2013/2949