N. C. Obitte

The Application of Factorial Experimental Design in Capsule Coating for Potential Colon Targeting of an Antiamebic Drug

N. C. Obitte & A. Chukwu · Journal of Pharmaceutical Research International · 2014

Aim: The application of factorial experimental design to evaluate the effect of particle size, capsule surface coating and binder concentration on the in vitro controlled release profile of metronidazole from encapsulated granules. Methodology: Metronidazole granules were prepare...

Open access Research Article 10.9734/BJPR/2014/7076

Optimized Artemether-loaded Anhydrous Emulsion

N. C. Obitte, L. C. Rohan, C. M. Adeyeye & C. O. Esimone · Journal of Pharmaceutical Research International · 2013

Objective: The objectives of this study were to identify stable anhydrous emulsions via pseudo ternary phase diagram, optimize artemether-loaded batches using factorial design and subsequently evaluate the antimalarial activity. Methodology: Using labrasol®, triacetin® and laurog...

Open access Research Article 10.9734/BJPR/2014/5279