The Impact of Modifying the Chemical Structure of Nalidixic Acid on the Antimicrobial Activity of Its Derivatives: A Review
Łukasz Popiołek & Monika Gawrońska-Grzywacz · International Research Journal of Pure and Applied Chemistry · 2015
Nalidixic acid was the first quinolone antibiotic introduced to the treatment of urinary tract infections. It was effective especially against Gram-positive and Gram-negative bacteria but resistance to it emerged rapidly. In this article we reviewed the newly synthesized nalidixi...
Open access
Research Article
10.9734/IRJPAC/2015/17634