Krabbe disease (or Globoid cell leukodystrophy) is a rare mutation of a gene found on chromosome 14q31 responsible for the production of the enzyme called galactocerebrosidase (G ALC), which breaks down two galactolipids; galactosyl-ceramide and galactosylsphingosine (psychosine)...
Adedeji Okikiade, Nourhan Abdulrahman, Miriam Tikanide, Jeffrey Ndu, Annah Akoth, Esther Akinyode, Twanna Browne-Caesar & Aromedonghene Osharode·Asian Journal of Research in Nephrology·2022
Alport syndrome (AS), also known as hereditary nephrosis, is an X-linked genetic disease that predominantly affects type IV collagen mainly in the kidneys and the eyes. It primarily affects males, particularly children, and can be transmitted via autosomal dominant and recessive...
Adedeji Okikiade, Edward Taylor, Norhan Abdulrahman, Oyeniyi Imoleayo, Miriam Tikanide, Aromedonghene Osharode & Damisola Ogunesan·International Research Journal of Oncology·2022
Paraneoplastic Neurological Syndromes (PNS) are a rare spectrum of non-metastatic manifestations likely secondary to T-cell or auto-antibodies induced neuronal dysfunction or cell death and are mostly associated with soft tissue cancers. PNS arises from either the cell membrane b...