Background: Psoriatic arthritis (PsA) is a chronic immune-mediated inflammatory disease that may be associated with extra-articular manifestations, including uveitis. Ocular involvement is uncommon in PsA and usually limited to anterior uveitis. Posterior uveitis complicated by s...
Open access
Research Article10.9734/jamps/2026/v28i5860
Background: While cytomegalovirus (CMV) infection is usually benign in immunocompetent adults, it can exceptionally trigger severe hematological autoimmunity. Case Presentation: We report the case of a 41-year-old immunocompetent woman admitted with profound symptomatic anemia (...
Open access
Research Article10.9734/ajrid/2025/v16i10497
Background: Horner syndrome (HS), a rare neurological condition caused by disruption of the oculosympathetic pathway, can occasionally serve as an early indicator of systemic diseases such as Behçet syndrome (BS). Neuro-Behçet syndrome (NBS) represents a severe manifestation of B...
Open access
Research Article10.9734/ijmpcr/2025/v18i2416
Tuberculosis is a bacterial infection caused by the Mycobacterium tuberculosis complex, which includes five Mycobacteriums : Tuberculosis (commonly known as Koch's Bacillus), Bovis, Africanum, Microti, and Pinnipedii. This condition affects both humans and certain animal species...
Open access
Research Article10.9734/ajrrop/2025/v8i1114
Syphilis is a sexually transmitted bacterial infection that first appeared in Europe in the 15th century, responsible for deadly epidemics before the discovery of penicillin. It typically progresses through three phases: primary syphilis, characterized by a syphilitic chancre tha...
Open access
Research Article10.9734/ajrid/2024/v15i10376
Background: Systemic lupus erythematosus (SLE) with onset after the age of 50 years accounts for approximately 10–20% of cases and is often associated with atypical clinical features and delayed diagnosis. Gastrointestinal involvement as an initial manifestation is uncommon, and...
Open access
Research Article10.9734/ajrrga/2026/v9i1214
Background: Muscular dystrophies (MDs) are a heterogeneous group of inherited disorders characterized by progressive muscle degeneration and weakness. Although most cases are diagnosed in childhood, late-onset forms may present during adolescence or adulthood and mimic inflammato...
Open access
Research Article10.9734/ajmpcp/2026/v9i1420
Bone marrow plasmacytosis is most commonly associated with plasma cell dyscrasias such as multiple myeloma; however, it may also arise as a reactive phenomenon in various clinical contexts. Distinguishing between these entities is particularly challenging in young adults, in whom...
Open access
Research Article10.9734/ajcrmh/2026/v9i1313
Introduction: Chronic granulomatous disease (CGD) is a rare inherited primary immunodeficiency characterized by defective oxidative metabolism of phagocytic cells. It is occasionally associated with autoimmune manifestations, including systemic lupus erythematosus (SLE). Sweet’s...
Open access
Research Article10.9734/ajcrmh/2025/v8i1265
Background: Thrombotic microangiopathy (TMA) is a rare but severe manifestation of systemic lupus erythematosus (SLE), frequently associated with antiphospholipid syndrome (APS). Early recognition is crucial, as it significantly influences renal and overall prognosis (George &...
Open access
Research Article10.9734/ajcrmh/2026/v9i1315
Behçet’s disease (BD) is a rare systemic vasculitis with an unclear etiology, infrequently associated with hematologic malignancies. We report a 27-year-old man with severe mucocutaneous BD who developed acute myeloblastic leukemia (AML-1) following a SARS-CoV-2 infection. The pa...
Open access
Research Article10.9734/ajcrmh/2025/v8i1234
Fibrodysplasia ossificans progressive (FOP) is a rare variety of myositis ossificans characterized by congenital malformations of the great toes and progressive heterotopic ossification that can induce a disabling second skeleton. We report a case of a 37-year-old female patient...
Open access
Research Article10.9734/ajcrmh/2025/v8i1214
Background: Golimumab, a human monoclonal antibody targeting tumor necrosis factor-alpha (TNF-α), is widely used to treat ankylosing spondylitis (AS). However, it can paradoxically trigger dermatological conditions, including psoriasis. This report details a rare instance of palm...
Open access
Research Article10.9734/ajcrmh/2025/v8i1237
We report a rare association of Late Onset Combined Immunodeficiency (LOCID) with epidermodysplasia verruciformis (EV) in a 23-year-old Moroccan woman. At age 7, the patient developed thousands of small verrucae and experienced recurrent respiratory and gastrointestinal infection...
Open access
Research Article10.9734/ajcrmh/2025/v8i1228
Werner syndrome (WS), or adult progeria, is a rare autosomal recessive disorder characterized by premature aging and multisystem involvement. Its initial presentation through a metabolic emergency remains exceptional. We report the case of a 41-year-old woman with a history of ch...
Open access
Research Article10.9734/ajcrmh/2025/v8i1230
Relapsing polychondritis (RP) is a rare, immune-mediated systemic disorder with an estimated prevalence of 4.5 to 20 cases per million population. It is characterized by recurrent inflammation of cartilaginous and proteoglycan-rich tissues, particularly affecting the auricles, na...
Open access
Research Article10.9734/ajcrmh/2025/v8i1224
Background: Thoracic involvement in Behçet’s disease (BD) is uncommon but is associated with significant morbidity and mortality, mainly due to vascular complications. Aim: This study aimed to evaluate thoracic manifestations of Behçet’s disease, excluding cardiac involvement, in...
Open access
Research Article10.9734/jamps/2026/v28i7871
Yassir Lakrafi, Benhayoun Basma, Cherfouf Rihabe, Bouroyene El Mehdi, Barakat Leila, Benzakour Merieme, Khadija Echchilali, Mina Moudatir & Hassan El Kabli·Asian Journal of Immunology·2024
Systemic sclerosis is a non-organ-specific autoimmune disease of the connective tissue, characterized by excessive production of collagen leading to fibrosis of the skin as well as organs such as the lung, it is responsible for aesthetic discomfort, an alteration of the functiona...
Open access
Research Article10.9734/aji/2024/v7i1140