Mikhail V. Dorogov

The Synthesis of Atomoxetine-containing Carboxamides - Potential Human Carbonic Anhydrase Inhibitors

Anton A. Shetnev, Angelina T. Osipyan, Alexander V. Sapegin & Mikhail V. Dorogov · Chemical Science International Journal · 2015

The method of synthesis of Atomoxetine is developed, including enzyme-catalyzed stereospecific reduction 3-chloro-1-phenyl-propan-1-one and Mitsunobu condensation with a chiral alcohol, and o-cresol. New potential human carbonic anhydrase inhibitors were obtained via reaction Ato...