Treat Oculocutaneous Albinism with Gene Therapy Oculocutaneous albinism (OCA) is a group of hereditary recessive disorder recognized as a loss of pigmentation. OCA can derive from mutations in different genes that produce melanin. These mutations cause disturbances to get a stand...
Open access
Research Article10.9734/JABB/2017/38504
Friedreich ataxia (FA) is a disorder in the nervous system inherited to the Mendel’s law. Mutations in the FXN gene trigger the FA disorder. The FXN gene occupies chromosome 9q21.11 in the chromosome map. Four classes of alleles are in the mutated FXN gene. These include normal a...
Open access
Research Article10.9734/JABB/2017/36113
Hemophilia A is a hemorrhage disorder inherited according to the X-linked inheritance pattern. It affects about 1 in 4,000 to 10,000 males. Permanent changes in the F8 gene result in hemophilia A. These changes result in an abnormal version of coagulation factor VIII. This abnorm...
Open access
Research Article10.9734/JABB/2017/35111