Mariana Babayeva

A Novel HPLC Method for Determination of Phenytoin in Human Plasma

Jesse Flores, Sheril Alexander & Mariana Babayeva · Journal of Pharmaceutical Research International · 2018

Aim: Aim of this research was to develop and validate a simple, efficient and reproducible high-performance liquid chromatography method to measure phenytoin concentrations in human plasma Study Design: Linearity, selectivity, sensitivity, accuracy and precision of the analytical...

Open access Research Article 10.9734/JPRI/2018/41885

Significant Inhibition of Protein Binding of Phenytoin

Sheril Alexander, Jesse Flores, Henrietta Ofuluozor & Mariana Babayeva · Journal of Advances in Medicine and Medical Research · 2018

Aim: This research was aimed to assess the potential for inhibition of protein binding of phenytoin by tizoxanide in human plasma. Phenytoin was used because studies have proven to be a highly plasma protein-bound drug with a narrow therapeutic index and non-linear pharmacokineti...

Open access Research Article 10.9734/JAMMR/2018/40729