Maria da Conceição Proença

Particle-Picking in Cryo-Electron Microscopy Images with Online Resources

Maria da Conceição Proença · Journal of Advances in Microbiology · 2023

Aims: Use deep learning online resources to identify and pick single particle views in micrographs to enable high quality three-dimensional reconstruction for macromolecular structure determination. Study Design: Using the keyhole limpet hemocyanin dataset, a public cryo electron...

Open access Research Article 10.9734/jamb/2023/v23i10765

Polyomavirus Localized with Deep Learning Methods

Maria da Conceição Proença · Journal of Advances in Microbiology · 2022

This case study shows how to apply a deep learning algorithm to detect specific particles in transmission electron microscopy images. The main difficulty consists in the confusing background where a mix of artifacts introduced by the negative staining method coexist with biologic...

Open access Research Article 10.9734/jamb/2022/v22i330445