Mansour Heidari

Impact of TGIFLX Expression on the Regulation of BCL2 and BAX in Prostate Cancer Cell Line (LNCaP)

Reza Raoofian, Majid Mojarrad & Mansour Heidari · Journal of Advances in Medicine and Medical Research · 2013

Aims: The homeoprotein TGIFLX (transforming growth factor-β-induced factor 2-like, X-linked), which is essential in male reproduction and development and likely oncogenic when aberrantly expressed in prostate. We have previously shown an aberrant expression of TGIFLX in the major...

Open access Research Article 10.9734/BJMMR/2013/2904

Digoxin Inhibits Retinoblastoma through Suppressing a Non-canonical TGFβ Signaling Pathway

Maryam Sheikhzade, Abolfazl Akbari, Reza Karkhaneh, Fariba Ghassemi, Abdolrahim Sadeghi, Mahshid Shahrzad Kavakani, Gholam Reza Mobini, Masoumeh Mohebbi & Mansour Heidari · Journal of Advances in Medicine and Medical Research · 2016

Aims: Retinoblastoma is a childhood ocular tumor rapidly developing from the immature cells of the retina due to loss of functional retinoblastoma protein. Digoxin, a cardiac glycoside, has been reported to be effective in inducing apoptosis, cell cycle arrest, and cytotoxic effe...

Open access Research Article 10.9734/BJMMR/2016/25709