Membrane Interactivity of Anesthetic Adjuvant Dexmedetomidine Discriminable from Clonidine and Enantiomeric Levomedetomidine
Maki Mizogami & Hironori Tsuchiya · Journal of Advances in Medicine and Medical Research · 2019
Aims: Dexmedetomidine, which has been increasingly used as an anesthetic adjuvant, is more lipophilic and more active than another α2-adrenergic agonist clonidine and enantiomeric levomedetomidine. Lipophilicity and stereostructure affect the clinical effects of α2-adrenergic ago...