Majd Almakhatreh

Therapeutic Role of Rosemary Extract against Vepesid Induced Kidney Injury, Proliferation and Apoptosis in Male Rats

Majd Almakhatreh, Thulfiqar Fawwaz Mutar & Ehab Tousson · Asian Oncology Research Journal · 2020

Background: Vepesid (Etoposide) is a chemotherapeutic agent used in many types of tumors, but use it in the treatment is limited because of its toxicity in normal organ tissues. However, rosemary (Rosmarinus officinalis) aqueous extract has shown a protective effect against cance...

Open access Research Article

Biochemical and Molecular Studies on the Role of Rosemary (Rosmarinus officinalis) Extract in Reducing Liver and Kidney Toxicity Due to Etoposide in Male Rats

Majd Almakhatreh, Ezar Hafez, Ehab Tousson & Ahmed Masoud · Asian Journal of Research in Medical and Pharmaceutical Sciences · 2019

Aims: Etoposide (Vepesid) is chemotherapeutic drugs that inhibit topoisomerase II activity and long been used for treatment of human malignancies, where it is a semi-synthetic compound derived from the plant Podophyllum peltatum. The current study was designed to investigate the...

Open access Research Article 10.9734/ajrimps/2019/v7i430126