Aim: To study acute and chronic toxicity profile of Commiphora opobalsamum (CO) in rats. Methods: Acute oral lethal effect and single oral dose toxicity of CO was determined in rats by comparison with standard control. In contrast repeated dose oral toxicity in rats were performe...
Open access
Research Article10.9734/jpri/2021/v33i19A31324
Background: The native herbal medicinal products are vital source of the key medication; their excellent dogmatic safety study is of prime importance despite their strong validated evidence of efficacy. Aim: To study the sub-acute toxicity of Commiphora opobalsamum (CO) by histol...
Open access
Research Article10.9734/jpri/2022/v34i26A35967
Dyslipidemia is usually observed in both types of diabetes and, particularly, “atherogenic dyslipidemic triad” is strongly linked to a higher risk of adverse cardiovascular outcome. On the other hand, bone morphogenetic proteins (BMP) are a group of wide variety of proteins which...
Open access
Research Article10.9734/jpri/2021/v33i51A33490
Aim: To determine the potential hepatoprotective effect of Agmatine (AGM) on NAFLD-induced by Type 2 diabetes mellitus (T2DM) in rats. Study design: Forty male Wistar rats weighing from (200 -250 g) were distributed at random into five groups (8 rats per group): group 1 as contr...
Open access
Research Article10.9734/jpri/2021/v33i31A31671
Background: Our recent past studies accomplished the target to investigate the anti-inflammatory effect as well as toxicological profile of Commiphora opobalsamum (CO), with almost identical potency in comparison to the contemporary anti-inflammatory drugs. This inspired us to ex...
Open access
Research Article10.9734/jpri/2021/v33i29A31574
Statins and thiazides which are widely prescribed for the treatment of hyperlipidemia and hypertension play an important role in bone metabolism and may have potential therapeutic implications for osteoporosis. Moreover, concomitant use of statins and thiazides may offer additiv...
Open access
Research Article10.9734/JPRI/2018/40943