Machindra J. Chavan

Formulation of Stable Nanoliposomes of Docetaxel: Design, Optimization, and in-vitro Characterization

Mallappa S. Harwalkar, Kishor S. Salunkhe, Machindra J. Chavan, Ravindra B. Chintamani & Raosaheb Sopanrao Shendge · Journal of Pharmaceutical Research International · 2020

Background: Liposome offers many advantages over conventional dosage forms, like increased bioavailability, possibility of releasing drug at slower and constant rate, accurate drug release. Docetaxel is approved by the FDA for the treatment of locally advanced or metastatic breas...

Open access Research Article 10.9734/jpri/2020/v32i3230940

Synthesis and Biological Activities of (4Z)-2-(1H-benzimidazol-2-ylmethyl)-4-arylidene-5-methyl-2,4-dihydro-3H-pyrazol-3-one Compounds

Vishal. S. More, Pranali A. Mishra, Nalanda T. Rangari, Bhaskar H. Vaidhun & Machindra J. Chavan · Journal of Pharmaceutical Research International · 2021

Pyrazoles are reported to be well known pharmacophores. This has motivated the synthesize some of the pyrazole derivatives by using hydrazine hydrate as well as adding benzimidazole in pyrazoles. A series of (4Z)-2-(1H-benzimidazol-2-ylmethyl)-4-arylidene-5-methyl-2,4-dihydro-3H-...

Open access Research Article 10.9734/jpri/2021/v33i63B35287