M. Y. Zaki

Uses of 2-Amino-5,6-dihydro-4H-cyclopenta [b] thiophene-3-carbonitrile in the Synthesis of Heterocyclic Compounds with Anticonvulsant, Behavioral and CNS Antidepressant Activities

K. A. El-Sharkawy, N. N. E. El-Sayed & M. Y. Zaki · International Research Journal of Pure and Applied Chemistry · 2012

The reaction of the cyclopenta[b]thiophene derivative 3 with phenylisothiocyanate4 gave thiourea derivative 5. The latter was reacted with the active methylene reagents 2a, b and 7 to give pyrimidine derivatives 6a, b and 8. N-Acylation of compound 3 was achieved via its reaction...