Synthesis of Some New Phthalimides as Anti-metabolic Agents with Chemotherapeutic Effects
Fathy A. Yassin, Amal F. Seleim, Ali M. Hassan, Atif F. Hadad, Nahed M. Fathy & M. Fayad · Journal of Pharmaceutical Research International · 2014
A series of new phthalimides 1(a-f) were synthesized via reaction phthalic anhydride with different amino acids under fusion conditions. Esterification of N-phthaloyl acid derivatives 1(a-f) with methanol in the presence of SOCl2 to producing the corresponding esters 2(a-f). Whic...
Open access
Research Article
10.9734/BJPR/2014/6355