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Luiz Costa

0009-0006-4580-9788

Publications (7)

The General Psychiatric Syndrome as a Transdiagnostic Hypothesis: A Critical Appraisal of Evidence, Interpretation and Clinical Reach

Luiz Costa, Fernando Martins Castanheira Júnior, Giovanna Azevedo Rodrigues & Marcelo Caixeta · International Neuropsychiatric Disease Journal · 2026

Persistent comorbidity, diagnostic instability and the scarcity of disorder-specific causes have encouraged the proposal that a single superordinate dimension underlies liability to all common mental disorders. This proposition, expressed empirically as the general factor of psyc...

Open access Research Article 10.9734/indj/2026/v23i5581

Psychiatric Complications Following Bariatric Surgery: Pathophysiological Mechanisms, Psychopathological Factors and Therapeutic Approaches

Luiz Costa, Ester Borges, Frinye Santos & Marcelo Caixeta · International Neuropsychiatric Disease Journal · 2026

Introduction: Bariatric surgery is a widely utilized intervention for the treatment of severe obesity; however, its effects extend beyond weight loss and may involve significant neurobiological and psychopathological alterations, potentially inducing or exacerbating psychiatric d...

Open access Research Article 10.9734/indj/2026/v23i1537

The Influence of Hormonal Contraceptive Use on Psychiatric Health

Luiz Costa, Samuel Ribeiro, Álvaro Vieira, Vivian Pereira, Ester Borges & Marcelo Caixeta · International Neuropsychiatric Disease Journal · 2025

Introduction: The use of hormonal contraceptives represents a significant advancement in reproductive health, offering effective contraception and the management of gynecological conditions. However, their effects on psychiatric health remain a subject of debate. This article aim...

Open access Research Article 10.9734/indj/2025/v22i5518

Haloperidol as a Novel Augmentation Strategy in Treatment-Resistant Depression: A Clinical Practice Perspective with Case Series

Giovanna Azevedo Rodrigues, Fernando Martins Castanheira Júnior, Luiz Costa & Marcelo Caixeta · Asian Journal of Research in Medical and Pharmaceutical Sciences · 2026

Treatment-resistant depression (TRD) remains a major clinical challenge when adequate antidepressant trials fail to achieve remission. This clinical practice perspective examines low-dose haloperidol as a potential augmentation strategy in carefully selected, treatment-refractory...

Open access Research Article 10.9734/ajrimps/2026/v15i4418

The Kinesthetic-motor Hypothesis in Developmental Dyslexia: A Systematic Review and Theoretical Model Proposition

Giovanna Azevedo Rodrigues, Fernando Martins Castanheira Júnior, Luiz Costa & Marcelo Caixeta · International Neuropsychiatric Disease Journal · 2026

Introduction: Developmental dyslexia is traditionally explained by the acoustic phonological deficit theory, yet clinical observations suggest that reading difficulties may extend to motor and articulatory components, manifesting as phono-articulatory stalls during the decoding o...

Open access Research Article 10.9734/indj/2026/v23i5577

Provisional Early-onset Bipolar Disorder with Phonological Reading Disorder and Attachment-related Difficulties in a Child Exposed to Severe Parental Conflict: A Case Report

Giovanna Azevedo Rodrigues, Fernando Martins Castanheira Júnior, Luiz Costa & Marcelo Caixeta · International Neuropsychiatric Disease Journal · 2026

Background: Severe mood dysregulation in childhood requires careful differentiation among episodic bipolar-spectrum illness, chronic irritability, trauma-related responses, anxiety, neurodevelopmental conditions, sleep disturbance, and environmental stress. Diagnostic uncertainty...

Open access Research Article 10.9734/indj/2026/v23i4572

Diagnostic and Differential Challenges of Psychoses in Adolescence: A Cognitive Perspective

Josimar Silva, Álvaro Vieira, Luiz Costa & Marcelo Caixeta · International Neuropsychiatric Disease Journal · 2025

Introduction: Adolescence is a period of high neuropsychological plasticity and vulnerability for the onset of psychotic symptoms. Diagnostic criteria validated in adults do not always capture the complex developmental dynamic and the overlap with anxiety, mood, and trauma, which...

Open access Research Article 10.9734/indj/2025/v22i5514