Severe and Prolonged Myelosuppression during Concomitant Temozolomide and Radiotherapy Treatment in a Patient with Glioblastoma Multiforme
Claudia Scaringi, Vitaliana De Sanctis, Giuseppe Minniti, Raffaele Porrini, Alessia Carnevale, Maurizio Valeriani, Maria Christina Cox, Maria Antonietta Aloe Spiriti, Giovanna Gentile, Maurizio Simmaco, Luigi Ruco, Agostino Tafuri & Riccardo Maurizi Enrici · International Journal of Medical and Pharmaceutical Case Reports · 2014
Aims: We describe the case of a patient with glioblastoma (GBM) who developed severe and prolonged myelosuppression during concomitant daily temozolomide (TMZ) and radiotherapy (RT) treatment. Analysis of polymorphisms in genes correlated with TMZ-induced myelotoxicity was also p...
Open access
Research Article
10.9734/IJMPCR/2015/13957