Aims: One of the ways to treat HIV/AIDS is Antiretroviral therapy (ART), which consists different schemes and includes numbers of drugs. However, in view of the HLA polymorphism it is necessary to determine the best association of ART with the HLA class II haplotypes. The purpose...
Open access
Research Article10.9734/BJMMR/2014/5664
Olegs Sabelnikovs, Liene Nikitina-Zake, Angelika Krumina, Zane Jaunberga, Janis Klovins, Ludmila Viksna, Lars J. Bjertnaes, Lilija Kovalchuka & Indulis Vanags·Journal of Scientific Research and Reports·2012
Aims: To determine whether an association exists between TNF-α 308 A/G, IL-6 174 G/C, and IL-10-1082 A/G promoter polymorphisms and the corresponding systemic cytokine concentrations and outcome in patients suffering from sepsis. Place and Duration of Study: The study was perform...
Open access
Research Article10.9734/JSRR/2012/1758
Aims: To find out the most frequent associations of the HLA II class loci DRB1*, DQA1*, DQB1* with the HIV/AIDS infection. Place and Duration of Study: The study took place in The Laboratory of Clinical Immunology and Immunogenetics (LCII) of Riga Stradiņš University (RSU), Riga...
Open access
Research Article10.9734/BJMMR/2014/8734
Aims: To find out whether ongoing missense mutations in the exon 2 of DRB1*01:01 affect the operation of this protective allele in HIV patients. Place and Duration of Study: the Clinical Immunology and Immunogenetics Laboratory of Riga Stradiņš University, Riga Eastern Clinical...
Open access
Research Article10.9734/BJMMR/2014/5660
Angelika Krumina, Ginta Vasiljeva, Andrejs Ivanovs, Sandra Gintere, Lilija Kovalchuka, Santa Rasa, Svetlana Chapenko, Modra Murovska, Ludmila Viksna & Inara Logina·Journal of Advances in Medicine and Medical Research·2014
Background and Objective: Chronic fatigue syndrome/myalgic encephalomyelitis (CFS/ME) remains a challenge for health care professionals because of its complex pathogenesis. Scales and questionnaires have been developed in order to assess the severity of syndrome. Fibromyalgia sha...
Open access
Research Article10.9734/BJMMR/2014/12225