The Chinese-Han Population Carrying Wild-type Genotypes of SLCO1B1 388A>G, SLCO1B1 521T>C, CYP3A4 1B, CYP3A4 1G, and CYP3A5*3 Exhibits a Significant Alteration in the Pharmacokinetics of Atorvastatin Calcium
Binbin Xia, Xianjun Liu, Yali Li, Yang Liu, Wenfang Sun, Jing Chen, Liushui Li, Jingyao Pang, Shicai Chen & Hua Cheng · Journal of Pharmaceutical Research International · 2023
Due to the diverse genetic characteristics of metabolism and high drug plasma exposure, great inter-subject variability exists in the clinical efficacy and incidence of adverse events. This study aimed to evaluate the associations between the SLCO1B1 388A＞G (rs2306283) polymorph...
Open access
Research Article
10.9734/jpri/2023/v35i277440