Lise A Koffi

Pharmacochemical Evolution of Carbapenems and Structural Analogues

Songuigama Coulibaly, Jean-Paul D.U. N'guessan, Apleheni E.M. Adouko, Jean-Fabrice K. Koffi, Lise A Koffi & Mahama Ouattara · Chemical Science International Journal · 2025

Carbapenems are a major class of antibiotics with a β-lactam nucleus that are distinguished by their effectiveness against many resistant pathogens. The discovery of Thienamycin, from Streptomyces cattleya, was the starting point for these antibiotics that revolutionized the trea...