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Léon Azefack Tapondjou

Publications (7)

Antisalmonella Activity and Modes of Action of Extracts, Fractions and Cerevisterol from Impatiens burtonii against Multi-Drug Resistant Salmonella

Aurelie Dahlia Yemeli Piankeu, Frank Wilson Tiatsop Kenmoe, Aimé Gabriel Fankam, Michel Noubom, Siméon Pierre Chegaing Fodouop, Rémy Bertrand Teponno, Léon Azefack Tapondjou & Donatien Gatsing · Microbiology Research Journal International · 2024

Background: Typhoid fever is an endemic disease in developing countries, especially throughout Asia and Africa, which may lead to life-threatening conditions in the absence of adequate treatment. Objective: This study was aimed at determining the in vitro activity of the crude ex...

Open access Research Article 10.9734/mrji/2024/v34i71458

Antibacterial, Anti-inflammatory and Antioxidant Activities of Senna alata and Commelina benghalensis Extracts

Vincent NGOUANA, Jean Polidor Nguetsa Demafo, Boniface Pone Kamdem, Brice Rostan Pinlap, Raoul Kemzeu, Simionne Lapoupée Kuitcha Tonga, Paul Keilah Lunga, Léon Azefack Tapondjou, Rémy Bertrand Teponno & Fabrice Fekam Boyom · Asian Journal of Research in Infectious Diseases · 2025

Background: Bacteria affecting the cutaneous-digestive and oral spheres, causing pain, inflammation and sometimes serious complications such as septicemia, are exacerbated by the emergence of new antibiotic-resistant strains. The World Health Organization (WHO) encourages the use...

Open access Research Article 10.9734/ajrid/2025/v16i12508

Acute and Subacute Toxicity Evaluation of the Methanolic Extract of Persea americana Mill

Vincent NGOUANA, Dorette Erica Tang Kenne, Boniface Pone Kamdem, Jaurès Marius Tsakem Nangap, Jean Polidor Nguetsa Demafo, Prisca Laure Nobosse Pewoupa, Armel Cyrille Tenkeu, Guy Sedar Singor Njateng, Léon Azefack Tapondjou, Rémy Bertrand Teponno & Fabrice Fekam Boyom · Asian Journal of Research in Botany · 2026

Background: The growing use of medicinal plants as an alternative therapy for a variety of diseases has gained significant attention, leading to increased scientific investigation into their bioactive compounds and pharmacological properties. However, the toxicity profile of such...

Open access Research Article 10.9734/ajrib/2026/v9i1314

Effects of Portulaca oleracea extract on Experimentally Induced Gastric Lesions in Wistar Rats: Antioxidative Action in Gastroprotection

Vincent NGOUANA, Prisca Laure Nobosse Pewoupa, Boniface Pone Kamdem, Jaurès Marius Tsakem Nangap, Raoul Kemzeu, Simionne Lapoupée Kuitcha Tonga, Guy Sedar Singor Njateng, Patrick Valère Tsouh Fokou, Léon Azefack Tapondjou, Rémy Bertrand Teponno & Fabrice Fekam Boyom · Asian Journal of Research in Biochemistry · 2025

Background: Gastric ulcer, a mucosal lesion resulting from an imbalance between aggressive factors (HCl, pepsin) and gastric defenses (mucus, bicarbonate, blood flow), remains a common pathology. Although treatments such as proton pump inhibitors (PPIs) and H2-receptor antagonist...

Open access Research Article 10.9734/ajrb/2025/v15i6459

In vitro Antifungal Activity of Crude Extracts from Commelina benghalensis and Senna alata on Selected Dermatophytes

Vincent NGOUANA, Jean Polidor Nguetsa Demafo, Boniface Pone Kamdem, Brice Rostan Pinlap, Raoul Kemzeu, Jaurès Marius Tsakem Nangap, Diana Sandra Wendji Monkam, Simionne Lapoupée Kuitcha Tonga, Guy Sedar Singor Njateng, Léon Azefack Tapondjou, Rémy Bertrand Teponno & Fabrice Fekam Boyom · Asian Journal of Research in Botany · 2025

Fungal infections of the skin, hair and nails represent a growing public health challenge due to their high global prevalence, the emergence of antifungal resistance, and the potential for severe, even fatal, complications in immunocompromised individuals. The World Health Organi...

Open access Research Article 10.9734/ajrib/2025/v8i2292

Phytochemical Screening, Antiplasmodial and Antioxidant Activities of Combretum rhodanthum Extracts

Vincent NGOUANA, Joseph Mbaku Ngoumou, Boniface Pone Kamdem, Aubin Kamche Youbi, Junelle MAKEMTEU, Marius Jaures Tsakem Nangap, Armel Cyrille Tenkeu, Raoul Kemzeu, Rémy Bertrand Teponno, Léon Azefack Tapondjou & Fabrice Fekam Boyom · South Asian Journal of Parasitology · 2025

Background: Plasmodium falciparum is responsible for over 90% of malaria cases and the vast majority of malaria-related deaths globally. Oxidative stress, an imbalance between free radicals and antioxidants, plays a key role in the malaria pathogenesis, potentially leading to inc...

Open access Research Article 10.9734/sajp/2025/v8i2214

Antiplasmodial and Antioxidant Activity of Vernonia blumeoides: A Medicinal Plant Used in Cameroon to Treat Malaria

Frank Lilian Mahel Batana, Vincent NGOUANA, Eugenie Aimée Madiesse Kemgne, Boniface Pone Kamdem, Marius Jaures Tsakem Nangap, Raoul Kemzeu, Junelle MAKEMTEU, Darline Dize, Patrick Valère Tsouh Fokou, Armel Cyrille Tenkeu, Paul Keilah Lunga, Rémy Bertrand Teponno, Léon Azefack Tapondjou & Fabrice Fekam Boyom · European Journal of Medicinal Plants · 2025

Background: Malaria is a parasitic disease that affects many parts of the globe, especially sub-Saharan Africa. Over time, malaria parasites have become resistant to most antimalarial drugs, including artemisinin. Medicinal plants, which are used in the traditional treatment of m...

Open access Research Article 10.9734/ejmp/2025/v36i21247