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Laxman J. Patel

Publications (4)

Development and Validation of New RP-HPLC Method for the Estimation of Antidiabetic Drugs Metformin Hydrochloride and Gemigliptin in Combined Pharmaceutical Dosage Form

Suleman S. Khoja & Laxman J. Patel · Journal of Pharmaceutical Research International · 2021

Metformin Hydrochloride and Gemigliptin is combination of Antidiabetic drug in tablet Zemimet SR ® Tablet (25/500 mg), a member Antidiabetic drug, is a recent drug developed by LG Life sciences for the treatment of Type 2 diabetes. A new sensitive and rapid HPLC method was develo...

Open access Research Article 10.9734/jpri/2021/v33i30B31649

Development and Validation of New Analytical LC-MS/MS Method for the Estimation of Antidiabetic Drugs Ertugliflozin and Sitagliptin in Combined Pharmaceutical Dosage form

Suleman S. Khoja & Laxman J. Patel · Journal of Pharmaceutical Research International · 2021

Ertugliflozin and Sitagliptin is combination of Antidiabetic drug in tablet Steglujan 15 mg/100 mg film-coated tablets®, a member Antidiabetic drug, is a recent drug developed by Merck Sharp and Dohme Company for the treatment of Type 2 diabetes. Ertugliflozin and Sitagliptin can...

Open access Research Article 10.9734/jpri/2021/v33i30A31631

Synthesis, Drug Likeness and In-vitro Screening of Some Novel Quinazolinone Derivatives for Anti-Obesity Activity

Pratik G. Modh & Laxman J. Patel · Journal of Pharmaceutical Research International · 2021

Aim: A series of novel quinazolinone derivates was synthesized and assessed for their ability to inhibitory action on pancreatic lipase. The cyclization of quinazolinone-4(3H)-one derivatives was achieved, whereas carbon-carbon cross coupling reactions were carried out on cyclize...

Open access Research Article 10.9734/jpri/2021/v33i28B31541

Synthesis, Analytical Characterization and Anti-Diabetic Activity of Some Heterocycles of Quinazolin-4(3H)one

Pratik G. Modh, Mitali H. Jasani & Laxman J. Patel · Journal of Pharmaceutical Research International · 2021

Aim: Novel quinazolin-4(3H)-one heterocycles were synthesized and assessed for their anti-diabetic activity. Non-enzymatic glycosylation of haemoglobin assay was carried out to identify their potential as anti-diabetic. The cyclization of quinazolinone-4(3H)-one heterocycles was...

Open access Research Article 10.9734/jpri/2021/v33i32B31744