Design, Synthesis, and Drug-Likeness Assessment of Azole-Functionalized Hydrazone Derivatives: Towards Antimicrobial Activity
Juozas Kiltinavičius, Kristina Kantminienė, Ilona Jonuškienė & Ingrida Tumosienė · Organics · 2026
Reaction of 5-oxo-1-(4-(phenylamino)phenyl)pyrrolidine-3-carbohydrazide with selected aldehydes and ketone provided novel hydrazone derivatives bearing azole moieties: pyrazole, pyrrole, and indole. The drug likeness of the newly synthesized compounds and their physicochemical ch...
Open access
Research Article
10.3390/org7020020