QSAR Modelling of Novel Coumarin Derivatives for MAO-B Inhibition
Konan René Kambo, Koffi Charles Kouman, Ludovic Akonan, Akoun Abou, Eugene Megnassan, Rita Kakou-Yao & Abodou Jules Tenon · Journal of Pharmaceutical Research International · 2024
We report here the design of new inhibitors against human monoamine oxidase (hMAO-B) as potential treatment of Parkinson’s disease. We have completed computer-aided molecular design of MAO-B inhibitors by In situ modification of the reference crystal structure of 7-(3-chlorobenzy...
Open access
Research Article
10.9734/jpri/2024/v36i107592