Koffi Alexis Respect Kouassi

Predictive Modeling of the Human Hepatoma (Huh-7D12) Cancer Line of a Series of bis- (5-arylidene-rhodanine-3-yl) Diamine

Koffi Alexis Respect Kouassi, Anoubilé Benié, Mamadou Guy-Richard Koné, Wacothon Karime Coulibaly, Kouadio Valery Bohoussou & Adenidji Ganiyou · Asian Journal of Chemical Sciences · 2019

This work deals with the prediction of the antiproliferative activity of eighteen (18) substances derived from bis-5-arylidene rhodanine against human hepatoma tumor line (Huh-7D12). By applying the functional density theory (DFT) method to the B3LYP / 6-31G (d, p) level, theoret...

Open access Research Article 10.9734/ajocs/2019/v6i218993

Identification of Potential Candida albicans Inhibitors Through Pharmacophore Modeling and Virtual Screening Techniques

Adenidji Ganiyou, Koffi Alexis Respect Kouassi, Essoh Akpa Eugene, N’Guessan Boka Robert & Kone Soleymane · International Research Journal of Pure and Applied Chemistry · 2025

Fungal infections have increased significantly in recent years and represent a major threat to human health. A large number of these infections are caused by the opportunistic pathogen Candida albicans. Lanosterol 14-alpha demethylase (CYP51), a critical enzyme in the cytochrome...

Open access Research Article 10.9734/irjpac/2025/v26i1899