Numerous studies have been carried out on the structure of 2,3-dihydro-1H-perimidine substituted as compounds with various biological activities. Researchers have found that these compounds exhibit characteristics potentially useful in medicinal chemistry research and have many t...
Open access
Research Article10.9734/CSJI/2021/v30i430227
In order to study the Quantitative Structure Activity Relationship (QSAR) against protein tyrosine phosphatase 1B and descriptors, we used a series of fourteen (14) molecules derived from perimidine. The compounds were optimized at the computational level B3LYP / 6-31 G (d, p), t...
Open access
Research Article10.9734/irjpac/2021/v22i830426
Tuo Nanou Tiéba, Pacôme Kouadio N’Go, BALLO Daouda, Kangah Niameke Jean Baptiste, Kodjo Charles Guillaume, Yapo Ossey Bernard & ZIAO Nahossé·Journal of Pharmaceutical Research International·2021
Background and Aim: The 1H-perimidne, as novel source carbene ligand, is well known for its anti-fungal, anti-microbial or anti-tumor activities. Here, we aimed to study the acute toxicity in Wistar rat of 2-(2,3-dihydro-1H-perimidin-2-yl)-6-methoxyphenol, a new heterocyclic 1H-...
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Research Article10.9734/jpri/2021/v33i24B31441
Ouattara Wawohinlin Patrice, Bamba Kafoumba, N’guessan Nobel Kouakou, Koné Mamadou Guy Richard, Kodjo Charles Guillaume & Nahossé Ziao·Asian Journal of Applied Chemistry Research·2019
The theoretical study of α-, β-, γ-, δ-, ε- MCl2(Azpy)2 isomers with (M = Fe, Os and Ru) complexes is carried out using Density Functional Theory (DFT) at the B3LYP / LANL2DZ level. This study is focused not only on the effect of metals over geometric, electronic and reactivity p...
Open access
Research Article10.9734/ajacr/2019/v3i130084