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Karunakar Shukla

Publications (3)

Design of a Reversible Cholinesterase Inhibitor Mamentine HCL Nanogel: Formulation and In-vitro Evaluation

Subhasri Mohapatra, Sourabh Jain & Karunakar Shukla · Journal of Pharmaceutical Research International · 2021

Memantine hydrochloride is a is a reversible cholinesterase inhibitor used in the treatment of Alzheimer’s disease, low-moderate affinity, uncompetitive n-methyl-d-aspartate (NMDA) receptor antagonist, with strong voltage dependency and rapid blocking/unblocking kinetics. The pre...

Open access Research Article 10.9734/jpri/2021/v33i41B32374

Formulation and Evaluationation of Anti-Alzheimer Drug MEM HCL Nanogel

Subhasri Mohapatra, Sourabh Jain & Karunakar Shukla · Journal of Pharmaceutical Research International · 2021

The object of present study was to formulate and evaluate MEM HCl loaded thermo sensitive in situ nanogel for 08 nasal delivery formulations. In present project a novel drug delivery system i.e. in situ polymeric gel was designed in the manner that the gel load MEM HCl in better...

Open access Research Article 10.9734/jpri/2021/v33i41A32332

Pharmacognostical Study, Phytochemical and Physicochemical Evaluation and Establishment of Quality Standards for Certain Traditional Antidiabetic Medicinal Plants

Sushilkumar Shinde, Sarin Chavhan, Saurabh Jain & Karunakar Shukla · Journal of Pharmaceutical Research International · 2021

Aim: The present work was aimed at evolving pharmacognostical and phytochemical quality standards for certain traditional herbs like Phyllanthus amarus, Glycerrhiza glabra and Piper nigrum. These three plants are reported to possess antidiabetic activity. Study Design: The plants...

Open access Research Article 10.9734/jpri/2021/v33i39B32207