Formulation and Evaluation of Sustained Release Matrix Tablets of Metformin Hydrochloride Using pH Dependent and pH Independent Methacrylate Polymers
Kamlesh J. Wadher, Rajendra B. Kakde & Milind J. Umekar · Journal of Pharmaceutical Research International · 2011
Metformin hydrochloride is recommended globally as first line therapy due to its favorable profile on morbidity and mortality associated with type-2 diabetes mellitus. However, limitations of multiple dosing and risk of triggering gastrointestinal symptoms make its dose optimizat...
Open access
Research Article
10.9734/BJPR/2011/255