Kalaiyarasi Dhamodharan

Capsaicin Encapsulated Chitosan Nanoparticles Augments Anticarcinogenic and Antiproliferative Competency Against 7,12 Dimethylbenz(a)anthracene Induced Experimental Rat Mammary Carcinogenesis

Kalaiyarasi Dhamodharan, Manobharathi Vengaimaran & Mirunalini Sankaran · Journal of Pharmaceutical Research International · 2021

Background: Capsaicin is a powerful phytochemical spotted in chilies, starkly tied up with a bunch of health benefits but its clinical applications in cancer therapy are limited due to its poor solubility, and low bioavailability. Nanotechnology offers a strategy to discover new...

Open access Research Article 10.9734/jpri/2021/v33i41A32311

Diosgenin Nanoparticles Competes Plain Diosgenin on Reviving Biochemical and Histopathological Alterations in DMBA Induced Rat Mammary Carcinoma via Modulating the AhR-Nrf-2 Signaling Cascades

Manobharathi Vengaimaran, Kalaiyarasi Dhamodharan & Mirunalini Sankaran · Journal of Pharmaceutical Research International · 2021

Background: Diosgenin, a steroidal saponin spotted as a primary ingredient in many traditional Chinese medicines, has sparked the attention of researchers owing to its multi-targeted cytotoxicity towards a multitude of cancers. Regrettably, its true potential was bounded by its i...

Open access Research Article 10.9734/jpri/2021/v33i47A32998