Neuroprotective Effects of Eleveted Dose Vitamin A on the Hippocampus of Adult Male Wistar Rats Exposed to Toxic Doses of Methamphetamine
Ezejindu Damian NNABUIHE, Joshua Izuchukwu ABUGU, Enemuo IJEOMA, Okeke Somadina Nnamdi, K. Ogbuokiri Doris, Okeke Henry Kachikwuru, Ekoh Augustine Alobu, Benedict Nzube Obinwa, Chinyere Elizabeth Eze, Nwaefulu Kester Eluemunor, Sobanke A. Omolara, Chidinma Ifeyinwa Mmaju, Okafor Anulika Jacinta, Chuka-Onwuokwu Ngozi Cynthia, Ejiogu Ikedichukwu Chibueze, Nwoko Sebastine Okechukwu, Wuraola Serah Nnaemeka, Ebi Victory Chinecherem, Agu Augustine Uchenna, Ugwu Augustus Uchenna, Nwodo Ndubuisi Francis, Elemuo Chukwuebuka Stanley, Agbai Johnson Ukwa, Muorah Chinecherem Onyekachi & Ozoemena Chiadikobi Lawrence · Asian Journal of Research in Medical and Pharmaceutical Sciences · 2026
Methamphetamine overstimulates brain regions such as the striatum and hippocampus by increasing neurotransmitter activity, thereby causing neurotoxicity, whereas vitamin A may help protect neurons through anti-inflammatory and neuroprotective effects. This study investigated the...