K. G. Huge

Synthesis of 3,4-dihydro -6-(2-hydroxy-5-(hydroxymethyl) phenyl)-4-phenylpyrimidine-2(1H)- Thione by Biginelli Approach

S. Y. Mane & K. G. Huge · Asian Journal of Chemical Sciences · 2026

Pyrimidine-2-thione derivatives are biologically active heterocycles widely explored in medicinal chemistry. The Biginelli reaction offers a simple and efficient route for their synthesis, driving interest in developing improved and environmentally friendly protocols.The developm...