Jose Isagani B. Janairo

Dipole Moment, Solvation Energy, and Ovality Account for the Variations in the Biological Activity of HIV-1 Reverse Transcriptase Inhibitor Fragments

Derick Erl P. Sumalapao, Jose Isagani B. Janairo & Nina G. Gloriani · Annual Research & Review in Biology · 2018

Objective: A computational approach was employed to determine the interaction of molecular descriptors and the biological activity of the different fragments of HIV-1 reverse transcriptase inhibitors (RTIs). Methods: Using multiple linear regression analysis and leave-one-out val...