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John A. Udobang

Publications (10)

Anti-Inflammatory Activity of Ethanol Root Extract of Panicum maximum

John A. Udobang, Jude E. Okokon, Daniel N. Obot & Utibe A. Edem · Asian Journal of Biology · 2020

Background: Panicum maximum root is used routinely to treat ailments such as malaria, fever, pains and inflammatory diseases by traditional medicine practitioners. Aim: The study evaluated the anti-inflammatory effect of P. maximum root so as to validate its uses by practitioners...

Open access Research Article 10.9734/ajob/2020/v10i230101

Toxicological Evaluation of Chronic Administration of Zea mays Husk Extract on Female Rats

Jude E. Okokon, John A. Udobang, Chinyelu C. Osigwe, Uwaeme Ugonma Florence & Mandu E. Nyong · Journal of Complementary and Alternative Medical Research · 2025

Zea mays L (Family-Poaceae) husk locally use as a remedy for various diseases was investigated for effect on hematological indices, liver and kidney functions as well as lipid profile and organs histologies after chronic administration of Zea mays ethanol husk extract to female W...

Open access Research Article 10.9734/jocamr/2025/v26i8693

Histopathological Study of Subacute Administration of Saccharum officinarum Leaf Extract on Some Organs of Rat

Jude E. Okokon, John A. Udobang, Chinyelu C. Osigwe, Uwaeme Ugonma Florence, Uduak P. Ise & Utibe A. Edem · Journal of Complementary and Alternative Medical Research · 2025

The leaves of Saccharum officinarum (Family-Poaceae) is employed traditionally for ethnotherapy of malaria and fever among others. Evaluation of subacute administration of Saccharum officinarum leaf extract for possible effect on organs of rats was carried out. The leaf extract (...

Open access Research Article 10.9734/jocamr/2025/v26i1611

In vivo Alpha Amylase and Alpha Glucosidase Inhibitory Activities of Hippocratea africana Root Extract and Fractions

Jude Efiom Okokon, John A. Udobang, Chinyere P. Chidiebere & Augustine I. Bassey · South Asian Journal of Parasitology · 2021

Aim: To study the in vivo alpha amylase and alpha glucosidase inhibitory activities of Hippocratea africana root extract and fractions. Methods: The root extract (200, 400, 600 mg/kg) and fractions (n-hexane, dichloromethane, ethyl acetate and methanol, 400 mg/kg) of H. africana...

Open access Research Article

Toxicological Assessment of a Polyherbal Mixture on Organ Weights and Hormonal Profile in Exposed Wistar Rats

Godswill J. Udom, John A. Udobang, Daniel N. Obot, Nkechi J. Onyeukwu, Ikanna E. Asuquo & Jude E. Okokon · Asian Journal of Research and Reports in Endocrinology · 2020

Hormonal imbalance and hypertrophy of internal organs are sensitive indices of toxicity which may be multifactorial (including exposure to certain foods, drugs and herbal remedies), and are implicated in certain conditions such as infertility amongst others. Dr Iguedo Goko Cleans...

Open access Research Article 10.9734/ajrre/2020/v3i129

Cytotoxic, In vitro and In vivo Antimalarial Activities of Hippocratea Africana

Jude E. Okokon, Paschal Amaechi, John A. Udobang & Hemant Kumar Bankhede · South Asian Journal of Parasitology · 2021

Aims: Analysis of cytotoxic effect, and correlation of in vitro and in vivo antimalarial activities of the root extract and fractions of H. africana so as to identify the active fraction. Methodology: The extract (200, 400, 600 mg/kg) and fractions (400 m/kg) were evaluated in mi...

Open access Research Article

Hepatotoxicity Assessment of a Polyherbal Mixture in Exposed Wistar Rats

Godswill J. Udom, Jude E. Okokon, John A. Udobang, Nkechi J. Onyeukwu, Daniel N. Obot & Ikanna E. Asuquo · Asian Journal of Research and Reports in Hepatology · 2020

The study evaluates the toxicity concern of a polyherbal mixture (Dr Iguedo Goko Cleanser®) on liver function parameters and liver histoarchitecture of exposed Wistar rats of both gender. Thirty (30) Wistar rats of both genders were randomly allotted to (6) six groups (5/group)....

Open access Research Article

Subchronic Toxicological Assessment of Dr Iguedo Goko Cleanser® on Lipid Profile and Serum Antioxidant Enzymes in Exposed Wistar Rats

Godswill J. Udom, Jude E. Okokon, John A. Udobang, Daniel N. Obot & Nkechi J. Onyeukwu · Asian Journal of Biology · 2020

Dr Iguedo Goko Cleanser® is a polyherbal mixture promoted as an effective herbal remedy for numerous diseases. Study aimed to evaluate the toxicity concern of the polyherbal mixture (PHM) on lipid profile and oxidative status in Wistar rats of both gender. Acute toxicity study wa...

Open access Research Article 10.9734/ajob/2020/v9i430093

Nephrotoxicity Assessment of Dr Iguedo Goko Cleanser® in Exposed Wistar Rats

Godswill J. Udom, Jude E. Okokon, John A. Udobang, Daniel N. Obot & Ikanna E. Asuquo · Asian Journal of Research in Medical and Pharmaceutical Sciences · 2020

Aims: This study was designed to evaluate the toxicity concern of Dr Iguedo Goko Cleanser® on kidney function parameters and histoarchitecture of the kidneys of exposed Wistar rats. Study Design: A 60-day subchronic toxicological assessment using animal model. Place and Duration...

Open access Research Article 10.9734/ajrimps/2020/v9i130144

Antipyretic Activity of Solanum anomalum Thonn. Ex Schumach Ethanol Leaf Extract in Rats

Chinyelu C. Osigwe, Jude E. Okokon, Ugonma F. Uwaeme & John A. Udobang · Journal of Complementary and Alternative Medical Research · 2025

Solanum anomalum Thonn. ex Schumach, belonging to the family Solanaceae is a medicinal plant used among various cultures especially in Africa. The fruits and leaves have been in use nutritionally and ethnomedically for the treatment of diabetes, gastrointestinal ailments, malaria...

Open access Research Article 10.9734/jocamr/2025/v26i8687