Joachim Ohiakwu Ezeadila

The Activity of Combination of Fluconazole with Ethanol Extracts of Some Medicinal Plants as Antifungals Against Some Clinical Candida species

Joachim Ohiakwu Ezeadila, Christian Chibuzo Uba, Onyekachukwu Izuchukwu Udemezue, Peace Chidimma Ilo, Christian Chinedu Orji & Chukwuebuka Chisom Anene · International Journal of Pathogen Research · 2025

The global threat posed by fungal infections has escalated significantly, with an increasing number of cases linked to drug-resistant pathogens, particularly among Candida species. Combining natural compounds with conventional treatments can be a more effective and less toxic for...

Open access Research Article 10.9734/ijpr/2025/v14i6412

In-vitro Antifungal Activity of Ethanol Plant Extracts of Moringa oleifera, Vernonia amygdalina and Ocimum gratissimum against Some Clinical Candida Species

Joachim Ohiakwu Ezeadila, Christian Chibuzo Uba, Onyekachukwu Izuchukwu Udemezue, Peace Chidimma Ilo, Christian Chinedu Orji & Chukwuebuka Chisom Anene · Microbiology Research Journal International · 2024

Vaginal candidiasis, primarily caused by microorganisms belonging to the Candida genus, is a common fungal infection prevalent among millions of women worldwide and can lead to significant morbidity. The treatment of Candida infections has often relied on antifungal drugs such as...

Open access Research Article 10.9734/mrji/2024/v34i101490

Antifungal Potency of Some Antifungal Chemotherapeutics and Antidandruff Solutions against Dermatophytic Flora from Local Hairdressers’ Tools in Awka, Nigeria

Joachim Ohiakwu Ezeadila, Peace Chidimma Ilo, Christian Chibuzo Uba & Onyekachukwu Izuchukwu Udemezue · Journal of Advances in Biology & Biotechnology · 2024

Dermatophytes produce spores that can survive for a long time on fomites such as hairdressing tools (combs, scissors, clippers and hairpins). These fomites intend serve in the transmission of dermatophytosis. This study was aimed at evaluating and comparing the antifungal efficac...

Open access Research Article 10.9734/jabb/2024/v27i6883

Antifungal Resistance Pattern of Candida Species Isolated from High Vaginal Swabs of Women Attending a Hospital in Enugu State, Nigeria

Joachim Ohiakwu Ezeadila, Ikechukwu Okoli & Christie Amaechi Oyeka · Journal of Advances in Microbiology · 2020

There is an increase in non-albicans Candida (NAC) vulvovaginal candidiasis which is attributed to overuse of antifungal therapy and this has led to antifungal resistance. This study was aimed at determining the antifungal resistance pattern of some clinical isolates of Candida s...

Open access Research Article 10.9734/jamb/2020/v20i930281

In vivo Antifungal Efficacy and Safety of Natural Compounds for Topical Treatment of Cutaneous Candidiasis

Onyekachukwu Izuchukwu Udemezue, Chidinma Princess Ezeamalu, Jennifer Somtochukwu Nwoye, Joachim Ohiakwu Ezeadila, Chukwuebuka Chisom Anene & Chizoba Quinette Igwilo · Journal of Advances in Microbiology · 2024

In vivo toxicity and antifungal therapeutic evaluation of selected natural compounds for topical applications was analyzed using standard methods. The natural compounds, blue vitriol, brimstone, trona, alum, palm ash and black stone were hygienically selected and purchased at a l...

Open access Research Article 10.9734/jamb/2024/v24i10852