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Jean-Fabrice K. Koffi

Publications (2)

Pharmacochemical Evolution of Carbapenems and Structural Analogues

Songuigama Coulibaly, Jean-Paul D.U. N'guessan, Apleheni E.M. Adouko, Jean-Fabrice K. Koffi, Lise A Koffi & Mahama Ouattara · Chemical Science International Journal · 2025

Carbapenems are a major class of antibiotics with a β-lactam nucleus that are distinguished by their effectiveness against many resistant pathogens. The discovery of Thienamycin, from Streptomyces cattleya, was the starting point for these antibiotics that revolutionized the trea...

Open access Research Article 10.9734/CSJI/2025/v34i1944

New Biological Targets in Fungi and Novel Molecule under Development: A Review

Songuigama Coulibaly, Jean-Paul D. U. N'guessan, Alain Kacou, Jean-Fabrice K. Koffi, Amelanh S. Diakité, Tanguy K. A. Kouaho & Mahama Ouattara · Chemical Science International Journal · 2021

Antifungal therapeutics is confronted today with the challenge of drug resistance of most fungal germs to current antifungal drugs. Faced with this situation, the search for new and more efficient antifungal molecules that avoid the phenomenon of drug resistance becomes an urgent...

Open access Research Article 10.9734/CSJI/2021/v30i630235