Jaqueline Ferreira Ramos

Synthesis, Biological Activity and Applications of 1,2,5-Oxadiazol: A Brief Review

João Rufino de Freitas Filho, Jucleiton José Rufino de Freitas, Juliano Carlo Rufino de Freitas, Clécio de Souza Ramos, Fabrícia Aparecida Marques de Souza, Jaqueline Ferreira Ramos, Ricarte Tavares & Drielly Emanoele Tomé Barros de Oliveira · International Research Journal of Pure and Applied Chemistry · 2023

Oxadiazoles are heterocyclic compounds that belong azole class which contain two nitrogen atoms and one oxygen, forming a five-membered heterocyclic ring. Four isomers of oxadiazoles are described in the literature. Among these, 1,2,4-oxadiazole, 1,2,5-oxadiazole, and 1,3,4-oxadi...

Open access Research Article 10.9734/irjpac/2023/v24i1798

A convenient Synthesis of 3-aryl-5-Hydroxyalkyl-1,2,4-oxadiazoles from a-hydroxy Esters and Amidoximes under Solvent-free Conditions

João Rufino de Freitas Filho, Jucleiton José Rufino de Freitas, Juliano Carlo Rufino Freitas, Aldicéia Luiz de Moura, Mauricélia Maria de Sousa Mata, André Ricardo França da Silva, Maria Verônica de Sales Barbosa & Jaqueline Ferreira Ramos · International Research Journal of Pure and Applied Chemistry · 2021

The present study aimed to synthesis and characterization of 3-aryl-5-hydroxyalkyl-1,2,4-oxadiazoles (5a-d, 6a-d, 7a/d, 8a-d and 9a-c). The 3-aryl-5-hydroxyalkyl-1,2,4-oxadiazoles were synthesized by treatment of arylamidoxime 1a-d with a-hydroxy esters for 4 hours without any so...

Open access Research Article 10.9734/irjpac/2021/v22i1130446