Ivan da Rocha Pitta

Anti-inflammatory, Antiarthritic and Antinociceptive Activities of 3,5-Disubstituted Thiazolidine Derivatives

Diana Jussara do N. Malta, Larissa Cardoso C. Araújo, Aline S.G Carrazoni, Fernanda Virginia B. Mota, Sandra Cabral da Silva, Maria Andrea de S. Carmino, Maria do Carmo A. Lima, Ivan da Rocha Pitta & Teresinha Gonçalves da Silva · Journal of Pharmaceutical Research International · 2014

Aims: The aim of this study was to investigate the anti-inflammatory, antiarthritic and antinociceptive effects of two thiazolidinedione derivatives: 3-(2-bromo-benzyl)-5-(4-methylsufonyl-benzylidene)-thiazolidine-2,4-dione (LPSF/GQ-125) and 3-(2,6-difluoro-benzyl)-5-(4-methylsuf...

Open access Research Article 10.9734/BJPR/2014/8736

Tegumental Changes in Adult Schistosoma mansoni Induced by a New Imidazolidinic Derivative

Anekécia Lauro da Silva, Sheilla Andrade de Oliveira, Jamerson Ferreira de Oliveira, Edna de Farias Santiago, Antônio Sérgio Alves de Almeida Júnior, Íris Trindade Tenório Jacobi, Christina Alves Peixoto, Vinícius Pinto Costa Rocha, Milena Botelho Pereira Soares, Ivan da Rocha Pitta & Maria do Carmo Alves de Lima · Journal of Pharmaceutical Research International · 2014

Aims: Verify the potential of the schistosomicidal imidazolidine derivative (5Z)-3-(4-bromo-benzyl)-5-(4-chloro-benzylidene)-4-thioxo-imidazolidin-2-one. Study Design: In this study, we tested the imidazolidinic derivative 3 through in vitro evaluations, cytotoxicity assay and an...

Open access Research Article 10.9734/BJPR/2014/12511

Activity Anti-Inflammatory and in silico Study of New Thiazolidinedione Derivatives

Laudelina R. de Magalhães, Iane Bezerra Vasconcelos Alves, Everaldo dos Santos, Vinícius Barros Ribeiro da Silva, Luiz Carlos Apolinário da Silva, Anekécia Lauro da Silva, Leidiane Carla Lira de Oliveira, Anne Cecília Nascimento da Cruz, Bruno Iraquitan Miranda da Silva, Lúcia Fernanda C. da Costa Leite, Marcelo Hernani Zaldini, Ivan da Rocha Pitta, Teresinha Gonçalves da Silva & Maria do Carmo Alves de Lima · Journal of Pharmaceutical Research International · 2014

Aims: Evaluation of the anti-inflammatory properties of new thiazolidine-2,4-diones derivatives. Study Design: Study the effects of new thiazolidine-2,4-diones derivatives on the inflammatory process. Place and Duration of Study: Departamento de Antibióticos, Universidade Federal...

Open access Research Article 10.9734/BJPR/2014/11294