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Innocent Effiom Offiong

Publications (6)

Effects of Vitamin C on Aluminum Chloride- Induced Neurotoxicity on the Hippocampal Cortex of Adult Wistar Male Rats

Innocent Effiom Offiong, Adeshina John Ajibade, Foluso Olamide Ojo, Kehinde Busuyi David & Folorunso Kolade Pelumi · Asian Journal of Medicine and Health · 2024

This study aimed to evaluate the neuroprotective effects of Vitamin C on aluminum chloride (AlCl₃)- induced brain damage, focusing on behavioral, biochemical, and histomorphological outcomes in a rodent model. Study Design: A total of 42 healthy male rats were randomly assigned t...

Open access Research Article 10.9734/ajmah/2024/v22i101106

Neuroprotective Effects of Moringa Oleifera Extract Against Cobalt Chloride-Induced Oxidative Damage in the Cerebellum of Male Wistar Rats

Isaac Oluwatobi Olaniyan, Adeshina John Ajibade, Innocent Effiom Offiong & Taiwo Oluseyi Adebayo · Asian Journal of Research in Medical and Pharmaceutical Sciences · 2025

Cobalt is an essential cofactor in the body, found in nutrients like vitamin B12. It has been reported that occupational exposure to cobalt chloride leads to neurodegeneration. Presently, neurodegenerative diseases have remains problems of global health concern which necessitates...

Open access Research Article 10.9734/ajrimps/2025/v14i1295

Effect of Cadmium Chloride Administration and Restraint Stress Model on Cardiac Function of Female Wistar Rats

Gbenga Opeyemi Owolabi, Esther Atinuke Jejelaye & Innocent Effiom Offiong · Asian Journal of Biology · 2024

Psychological stress which is becoming an epidemic due to continental economic meltdown, wars, climate change, disasters has reached a point of global health concern and can be mimicked in rats by restraint stress model. Cadmium chloride is a heavy metal salt whose exposure can b...

Open access Research Article 10.9734/ajob/2024/v20i12463

Effects of Restraint Stress and Cadmium Chloride on the Liver Function of Female Wistar Rats (Rattus norvegicus)

Gbenga Opeyemi Owolabi, Onaopepo Abdulwakeel Lawal, Innocent Effiom Offiong & Aliyat Nafiu Olanrewaju · Asian Journal of Medicine and Health · 2024

Cadmium (Cd) and prolonged exposure to stress are associated with adverse health outcomes. Various studies have shown the impacts of stress and metal exposures on liver function. Cd is a non-redox metal, one of the important mechanisms underlying its toxicity is oxidative stress...

Open access Research Article 10.9734/ajmah/2024/v22i121131

Cadmium Chloride Induced Cognitive Decline in Female Wistar Rats Exposed to Chronic Restraint Stress

Gbenga Opeyemi Owolabi, Toluwalase Oyenike Oyewale, Richard Adedamola Ajike, Innocent Effiom Offiong & Aliyat Nafiu Olanrewaju · Asian Journal of Research in Medical and Pharmaceutical Sciences · 2024

Cadmium (Cd) is known to have some adverse effects on different biochemical and physiological functions causing neurotoxicity leading to neurodegeneration and increasing the risk factor for neurodegenerative disorders. Restraint stress is also associated with changes in behaviora...

Open access Research Article 10.9734/ajrimps/2024/v13i4279

Effect of Restraint Stress and Cadmium Chloride Administration on Cerebral Antioxidants in Female Wistar Rats

Gbenga Opeyemi Owolabi, Toluwalase Oyenike Oyewale, Esther Atinuke Jejelaye, Dorcas Oluwaseun Osinaike & Innocent Effiom Offiong · Asian Journal of Advanced Research and Reports · 2024

Cadmium is a toxic heavy metal which promotes oxidative stress in various organs including the brain. Restraint stress is a model of stress which involves physical constraint to induce homeostatic imbalance. This study aimed to evaluate the interaction of restraint stress and cad...

Open access Research Article 10.9734/ajarr/2024/v18i12828