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Ikalo David Oseghale

Publications (13)

Comprehensive Ethnomedicinal and Phytopharmacological Review of Jatropha tanjorensis

Ikalo David Oseghale, Godwin Mmaduabuchi Ikokwu, Osedebamen Hilary Ralph-Okhiria, Praise ODUNVBUN & Adeola Munirah ADEDOTUN · Asian Journal of Research in Biochemistry · 2025

Background: Jatropha tanjorensis is a medicinal shrub widely used in Nigerian traditional medicine. It contains bioactive compounds like polyphenols, saponins, and alkaloids, which are responsible for its antioxidant, anti-inflammatory, antidiabetic, and hepatoprotective effects....

Open access Research Article 10.9734/ajrb/2025/v15i4407

Ethnomedicinal and Phytopharmacological Aspects of Vernonia amygdalina (Bitter Leaf) Utilized as a Traditional Medicinal Herb

Ikalo David Oseghale, Olabisi Promise Lawal, Daniel Osezuwa Ubebe, Vivian Chidera Orjiewulu, Aimuanmwosa Andrew Igunma, Omali Patricia Odey, Dorcas Temitope Ajibola, Divine Ibecheozor Chima, Nwigbo Kiakpugi Tuador & Chinaemerem Precious Ani · Asian Journal of Research in Biochemistry · 2024

Vernonia amygdalina Delile, commonly known as “bitter leaf,” is a shrub in the Asteraceae family, widely seen in tropical regions of Africa. Vernonia amygdalina is found to be traditionally used in African medicine. Various parts of this plant, especially the leaves, are utilized...

Open access Research Article 10.9734/ajrb/2024/v14i6326

Metastasis in Cancer and Tumor Cells

Ikalo David Oseghale, Godwin Mmaduabuchi Ikokwu & Uyinonijesu Diamond Victor-Ogie · International Research Journal of Oncology · 2023

A crucial stage in the development of cancer is metastasis, which greatly increases patient morbidity and mortality. The process of metastasis involves several steps, starting with the local invasion of cancer cells into the surrounding tissues, then extravasation, colonization a...

Open access Research Article

Dormacy in Cancer and Tumor Cells

Ikalo David Oseghale, Godwin Mmaduabuchi Ikokwu & Imade Omoregie · International Research Journal of Oncology · 2023

The phenomenon of dormancy in cancer and tumor cells is defined by the halting of cell division and the preservation of a dormant or slow-growing condition. Cells can stay in this state long after the underlying tumor has been excised or after surveillance and therapeutic interve...

Open access Research Article

Molecular Imaging for Early Cancer Diagnosis

Ikalo David Oseghale, Imade Omoregie & Godwin Mmaduabuchi Ikokwu · International Research Journal of Oncology · 2023

Molecular imaging is quickly gaining acceptance as a technique that has the potential to enhance every aspect of cancer treatment. Oncologists use molecular imaging to characterize and measure important biomolecules and molecularly based events that are essential to the malignant...

Open access Research Article

A Review of the CRISPR/Cas System and Its Potential for Early Cancer Diagnosis

Ikalo David Oseghale, Imade Omoregie, Courage Ushiobafoh Godday, Virtue Oniso Okhemukhokho & Godwin Mmaduabuchi Ikokwu · International Research Journal of Oncology · 2022

The range of CRISPR-based gene editing and modification technologies has quickly increased in recent years. In recent years, CRISPR/Cas has widened its application to diagnostics. CRISPR/Cas has the capacity to evade off targeting, which makes it both a powerful therapeutic tool...

Open access Research Article

Cancer Theranostics: An Emerging Field for Cancer Research, Diagnosis and Therapy

Ikalo David Oseghale, Courage Ushiobafoh Godday, Godwin Mmaduabuchi Ikokwu & Virtue Oniso Okhemukhokho · International Research Journal of Oncology · 2022

According to the World Health Organization (WHO) report in 2022, cancer is a leading cause of death worldwide, accounting for nearly 10 million deaths in 2020, or nearly one in six deaths, with cases amounting to breast cancer (2.26 million cases), lungs cancer (2.21 million case...

Open access Research Article

Emerging Trends in Antimicrobial Resistance and Novel Therapeutic Strategies

Godwin Mmaduabuchi Ikokwu, Ikalo David Oseghale, Imade Omoregie, Osedebamen Hilary Ralph-Okhiria & Esosa Frances Ighile · International Journal of Pathogen Research · 2023

Antimicrobial resistance (AMR) is a growing concern worldwide, as it can make  many commonly used antibiotics ineffective against bacterial infections. AMR occurs due to the emergence of new and more resistant bacterial strains and the misuse and overuse of antibiotics. Therefore...

Open access Research Article 10.9734/ijpr/2023/v12i3226

Protecting Your Health: A Comprehensive Review of Sexually Transmitted Illnesses

Godwin Mmaduabuchi Ikokwu, Ikalo David Oseghale, Osedebamen Hilary Ralph-Okhiria & Esosa Frances Ighile · International STD Research & Reviews · 2023

Sexually transmitted Infections are a class of diseases that are spread through sex. They can infect anyone who is sexually active regardless of age, gender, or sexual orientation. Common STIs include gonorrhea, syphilis, herpes, HIV/AIDS, and human papillomavirus (HPV).Many STIs...

Open access Research Article 10.9734/ISRR/2023/v12i1154

A Brief Review on Tumor Immunology

Ifeanyi Chukwurah, Ikalo David Oseghale, Godwin Mmaduabuchi Ikokwu & Chidimma Abigail Ezeokoli · International Research Journal of Oncology · 2023

The human immune system can eliminate unidentified proteins and contaminated tissues because it can discriminate between self and non-self proteins. The potential for cancer immunotherapy is largely predicated on the idea that cancer cells express particular antigens recognized b...

Open access Research Article

Dostarlimab: A Review of Its Pharmacology and Clinical Use in Management of Cancer

Busayo Odunayo Akodu, Azike Ruth Chinazor, Ikalo David Oseghale, Regina Titilayo Oddiri, George Chigozie Njoku & Godwin Okoye · International Research Journal of Oncology · 2022

According to the World Health Organization, cancer is the biggest cause of mortality globally, accounting for almost 10 million deaths in 2020, or nearly one in every six deaths (WHO). Breast (2.26 million instances), lung (2.21 million cases), colon and rectum (1.93 million case...

Open access Research Article

The Impact of Antimicrobial Resistance on Cancer Treatment: A Systematic Review of Current Evidence and Future Directions

Olabisi Promise Lawal, Nurain Kehinde Ahmed, Taiwo Ayomide Ilesanmi, Godswill Imolele Anthony, Samuel Nzube Nwosu, Festus Oladayo Ogungbemiro, Zainab Olaide, Muritadoh Muritadoh Adeniyi, Uchechukwu Lilian Okoye, Adebiyi Mutiat Olufunmilayo, Adegbesan Abiodun Christopher & Ikalo David Oseghale · Asian Journal of Research in Medical and Pharmaceutical Sciences · 2024

Background: Antimicrobial resistance (AMR) has emerged as a critical global challenge, posing substantial implications for managing infectious diseases and impacting treatment efficacy across diverse medical conditions, including cancer. Cancer patients are often susceptible to b...

Open access Research Article 10.9734/ajrimps/2024/v13i4270