Controlling Site Selectivity in the Phosphorylation of Amphiphilic Diols: Aminopyridine Organocatalysts vs. Stoichiometric Amine Bases
Shai Ben Sasson, Noa Naama, Mikhail Kozlov, Ibrahim Amer & Moshe Portnoy · Organics · 2026
Our recent studies demonstrated that dialkylaminopyridine organocatalysts featuring an extensive secondary sphere preferentially phosphorylate the alcohol at the apolar domain of a model amphiphilic diol. In the present study, this site-selective behavior was corroborated across...
Open access
Research Article
10.3390/org7020025