Henrietta Ofuluozor

Significant Inhibition of Protein Binding of Phenytoin

Sheril Alexander, Jesse Flores, Henrietta Ofuluozor & Mariana Babayeva · Journal of Advances in Medicine and Medical Research · 2018

Aim: This research was aimed to assess the potential for inhibition of protein binding of phenytoin by tizoxanide in human plasma. Phenytoin was used because studies have proven to be a highly plasma protein-bound drug with a narrow therapeutic index and non-linear pharmacokineti...