Drug interactions can have desired, reduced or unwanted effects. The probability of interactions increases with the number of drugs taken. Side effects or therapeutic drug interactions can increase or decrease the effects of one or two drugs. Failure may result from clinically me...
Open access
Research Article10.9734/jpri/2019/v26i130128
Mustafa Lawar, Safia Elbadwe, Ismail Yalçin, Kayhan Bolelli, Hakan Sezgin Sayiner & Fatma Kandemirli·Asian Journal of Chemical Sciences·2019
The pKa values were calculated for some acetoxy group molecules using CBS-Q method which is one of the Complete Basis Set methods to find accurate energies. The acetoxy group molecules were also planned by Quantitative Structure Activity Relationship (QSAR) to study their effect...
Open access
Research Article10.9734/ajocs/2019/v6i218991
Mustafa Lawar, Safia Badwe, Ismail Yalçin, Kayhan Bolelli, Hakan Sezgin Sayiner & Fatma Kandemirli·Asian Journal of Chemical Sciences·2018
QSAR analysis of thiosemicarbazone derivatives exposing RNR inhibitory activities [1] was performed for 21 compounds. Among these compounds, 13 of them were reported with inhibitory concentration (IC50) in the l M range. The inhibitory concentration of those compounds was convert...
Open access
Research Article10.9734/AJOCS/2018/42832