5HT1a Receptor Binding Affinities of a Series of Serotonin Transporter (SERT) Inhibitors and Related Thermodynamic Insights^
Gisella E. Alfonsino, Andrea Santagati, Livia Basile, Ettore Novellino, Corey Gaul, Carley Squires, Michael Braden, John M. Gerdes, Silvia Pérez Silanes, Salvatore Guccione & Keith K. Parker · Journal of Advances in Medical and Pharmaceutical Sciences · 2015
Clinical depression encompasses a complex neurobiology involving multiple interacting systems. This intricate pathophysiology is, in part, correlated with dysfunction in serotonin (5HT) neurochemistry. The 5HT1a receptor (R) and SERT (serotonin transporter) components of this net...
Open access
Research Article
10.9734/JAMPS/2015/18917