This article mainly reviews the recent developments in the synthesis of novel 1,3,4-Thiadiazoles and also recent development of drug molecules for the treatment of COVID-19. The Thiadiazole heterocycle and its derivatives are the most important class of compounds among various he...
Open access
Research Article10.9734/jpri/2021/v33i64B36210
An efficient synthetic process for an antispasmodic drug and active pharmaceutical ingredient of Mebeverine hydrochloride 1 is reported in this communication. It is used for stomach cramps and irritable bowel syndrome (IBS). The treatment for irritable bowel syndrome involves lot...
Open access
Research Article10.9734/jpri/2021/v33i57B34063
The main aim of the present study to Synthesize,method development and method validation for quantification of two potential genotoxic impurities i.e., Methyl(Z)-2-ethoxy-1-((2'-(N'-hydroxycarbamimidoyl)-[1,1'-biphenyl]-4-yl) methyl)-1H-benzo[d]imidazole-7-carboxylate(Impurity-A)...
Open access
Research Article10.9734/jpri/2021/v33i63A36047
Synthesis of Phenyl ethylene derivatives (4a-4f ) are reported in this communication. Products were characterized by1HNMR, Carbon (13C) NMR and Mass spectral data. Synthesized compounds of 4a-4f were screened for anti cancer and anti fungal activities and their results are prese...
Open access
Research Article10.9734/jpri/2021/v33i60B34801