Skip to content
G

G. O. Mbaka

Publications (7)

Antihyperglycaemic and Antihyperlipidaemic Activities of Aqueous Ethanol Root Extract of Pseudocedrela kotschyi on Alloxan-Induced Diabetic Rats

G. O. Mbaka, A. O. Ojewale, S. O. Ogbonnia & D. A. Ota · Journal of Advances in Medicine and Medical Research · 2014

Aim: To evaluate the antihyperglycaemic and antihyperlipidaemic properties of Pseudocedrela kotschyi in alloxan induced diabetic rats. Materials and Methods: Fasting blood glucose (FBG) was conducted by first inducing diabetes through intraperitoneal administration of alloxan mon...

Open access Research Article 10.9734/BJMMR/2014/7940

Acute and Sub-acute Toxicity Studies of Ethanol Seed Extract of Raphia hookeri on Swiss Albino Rats

G. O. Mbaka, S. O. Ogbonnia & F. O. Awoyemi · Journal of Pharmaceutical Research International · 2014

Aim: To evaluate the acute and sub-acute toxicities of Raphia hookeri (Rh) seed hydroethanolic extract on experimental animals. Materials and Methods: Acute toxicity study was evaluated on Swiss albino mice of both sexes. Administration of a single dose of 4000mg/kg of Rh seed ex...

Open access Research Article 10.9734/BJPR/2014/9330

Effect of Raphia hookeri Seed Extract on Blood Glucose, Glycosylated Haemoglobin and Lipid Profile of Alloxan Induced Diabetic Rats

G. O. Mbaka, S. O. Ogbonnia, K. J. Oyeniran & P. I. Awopetu · Journal of Advances in Medicine and Medical Research · 2012

Aim: To examine the effect of Raphia hookeri (RH) seed extract on blood glucose, glycosylated haemoglobin and lipid profile of alloxan induced diabetic rats. Materials and Methods: In the oral glucose tolerance test (OGTT), the animals received the extract (1 g/kg) or glibenclami...

Open access Research Article 10.9734/BJMMR/2012/1468

Evaluation of Haematinic Activity and Subchronic Toxicity of Sphenocentrum jollyanum (Menispermaceae) Seed Oil

G. O. Mbaka & M. A. Owolabi · European Journal of Medicinal Plants · 2011

Aim: The haematinic activity and subchronic toxicity of Sphenocentrum jollyanum (Menispermaceae) seed oil was evaluated and compared with the control. Materials and Methods: In acute toxicity study the animals tolerated up to 16 g/kg body weight (bw) of the extract in 2 % Tween 8...

Open access Research Article 10.9734/EJMP/2011/333

Toxicological, Histopathological and Purity Evaluation of Polyherbal Drug Katoka Mixtures in Rodents

S. O. Ogbonnia, G. O. Mbaka, H. I. Igbokwe, J. E. Emordi & D. A. Ota · Journal of Advances in Medicine and Medical Research · 2017

Aim: To conduct toxicological, histopathological and purity evaluation on Katoka® an herbal mixture in rodents. Materials and Methods: Microbial purity was evaluated on some bacterial and fungal organisms. Toxicity of the drug was on Swiss mice administered with graded doses of t...

Open access Research Article 10.9734/JAMMR/2017/32892

Evaluation of Microbial Purity and Acute and Sub-acute Toxicities of a Nigerian Commercial Polyherbal Formulation Used in the Treatment of Diabetes Mellitus

S. O. Ogbonnia, G. O. Mbaka, A. M. Nwozor, H. N. Igbokwe, A. Usman & P. A. Odusanya · Journal of Pharmaceutical Research International · 2013

Objective: This study evaluated acute and sub-acute toxicities in rodents and microbial purity of a polyherbal formulation, Bobwell® popular among the natives for the management of diabetes mellitus (DM). It was prepared with unspecified quantities of the following plant material...

Open access Research Article 10.9734/BJPR/2013/4117

Evaluation of Histomorphological, Toxicological and Antimicrobial Activities of Ethanolic Extract of Calliandra portoricensis Root in Rodents

V. N. Enwuru, S. O. Ogbonnia, G. O. Mbaka, J. E. Emordi, D. A. Ota & P. Onyebuchi · Journal of Pharmaceutical Research International · 2017

Objective: To evaluate histomorphological, toxicological and antimicrobial activities of ethanolic extract of Calliandra portoricensis root in rodents. Introduction: C. portoricensis is usually administered for a lengthy period in treating diseases like dysmenorrheal, rheumatism...

Open access Research Article 10.9734/JPRI/2017/34701