Background: Alzheimer’s disease (AD) is a neurodegenerative disorder characterised by progressive dementia, neuroinflammation, and the accumulation of intracellular neurofibrillary tangles and extracellular amyloid plaques. Oxidative stress and cholinergic dysfunction are key con...
Open access
Research Article10.9734/ijr2h/2026/v9i2244
Background: Alzheimer’s disease (AD) is a progressive neurodegenerative disorder characterised by cognitive decline, memory impairment, and oxidative stress. Aim: This study investigated the neuroprotective effects of the butanol fraction of Zapoteca portoricensis root (BFZP) in...
Open access
Research Article10.9734/ajorrin/2026/v9i1193
Felix Keneolisa Asogwa, Daniel Lotanna Ajaghaku, Augustine Oluchukwu Asogwa, Celestine Obiora Ugwu, Detu Martins Ikpechukwu, Kingsley Chidiebere Ndu & Linus Odinakachukwu Nsude·International Journal of Pathogen Research·2025
Probiotics are live microorganisms that, when administered in adequate amounts, confer health benefits to the host. Their impact on drug bioavailability and efficacy, particularly in gastrointestinal disorders, has gained considerable interest. This paper explores how probiotics...
Open access
Research Article10.9734/ijpr/2025/v14i3367
Felix Keneolisa Asogwa, Daniel Lotanna Ajaghaku, Augustine Oluchukwu Asogwa, Levi Onyebuchi Idokoja, Detu Martins Ikpechukwu & Damian Chukwunonso Mbah·International Neuropsychiatric Disease Journal·2025
Schizophrenia is a disorder characterized by a multifaceted pathogenic mechanism impacted by numerous genes. The investigation of its pathophysiology is mostly dominated by the dopamine hypothesis. Multi-target therapies represent a viable strategy for addressing polygenic disor...
Open access
Research Article10.9734/indj/2025/v22i4492
The medical term for elevated blood pressure is hypertension (HTN). It is risky because it puts too much strain on the heart and causes atherosclerosis, which is the hardening of the arteries, in addition to raising the risk of heart disease and stroke. Other diseases like, conge...
Epilepsy is a central nervous system (neurological) disorder characterized by a bizarre feelings, sensations, and behaviors. Muscle spasms, convulsions, and loss of consciousness occasionally from epileptic seizures. Neuronal dependent on neurotransmitters in the central nervous...
Open access
Research Article10.9734/indj/2022/v18i3355
Epilepsy is a neurological condition that affects the central nervous system and is characterized by strange emotions and actions. Antioxidants are believed to play a very vital role in the body defense system against reactive oxygen species (ROS). ROS, is a basal cause of aging...
Open access
Research Article10.9734/ajrimps/2025/v14i2302
Jude Ibeabuchi Ali, Felix Keneolisa Asogwa, Celestine Obiora Ugwu, Hannah Ndidiamaka Okorie, Treasure Nonye Ujam, Onyeka Chinwuba Obidiegwu & Festus BC Okoye·Asian Plant Research Journal·2024
Many diseases are treated using medicinal plants because they contain components that have therapeutic properties. The prevention and treatment of diseases linked to oxidative stress depend heavily on antioxidants. With over 20 genera and 600 species, the Combretaceae family is a...
Open access
Research Article10.9734/aprj/2024/v12i3253
Background: Epilepsy is a neurological illness that affects people of all ages and is characterized by excessive electric activity in the brain. This causes social embarrassment coupled with side effect of orthodox medication; hence, the needs to search for plant with antiepilept...
Open access
Research Article10.9734/jamps/2022/v24i8572