Simultaneous Quantification of Mesalamine and Its Metabolite N-Acetyl Mesalamine in Human Plasma by LC-MS/MS and Its Application to a Bioequivalence Study
Kanchanamala Kanala, Nagiat T. Hwisa, Babu Rao Chandu, Fathi H. Assaleh, K. Mukkanti, Prakash Katakam & Bala Sekhara Reddy Challa · Journal of Pharmaceutical Research International · 2014
Liquid chromatography–tandem mass spectrometry (LC–MS/MS) was used for simultaneous quantification of mesalamine and its metabolite N-acetyl mesalamine in human plasma with N-acetyl mesalamine D3 as an internal standard (IS). Chromatographic separation was performed on a Thermo,...
Open access
Research Article
10.9734/BJPR/2014/5350