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F. O. Taiwo

Publications (8)

Design, Synthesis and Biological Evaluation and Molecular Docking Study of (Z)-7-Nitro-1-Phenyl-3-((2-((1-Phenylethylidene) Amino) Ethyl) Amino) Quinoxalin-2(1H)-One Derivatives

F. O. Taiwo, O. B. Omoyeni, I. J. Olawuni, E. G. Fakola & Craig A. Obafemi · Journal of Pharmaceutical Research International · 2026

Aims: To synthesize  (Z)-7-nitro-1-phenyl-3-((2-((1-phenylethylidene)amino)ethyl)amino)quinoxalin-2(1H)-one derivatives and evaluate their possible biological properties. Methods: The substituted (Z)-7-nitro-1-phenyl-3-((2-((1-phenylethylidene)amino)ethyl)amino)quinoxalin-2(1H)-o...

Open access Research Article 10.9734/jpri/2026/v38i97867

Design, Synthesis and Biological Evaluation of (Z)-N,N-dibenzyl-3-oxo-2-((2-((1 phenylethylidene) amino)ethyl)amino)-3,4-dihydroquinoxaline-6-sulfonamide Derivatives

F. O. Taiwo, O. B. Omoyeni, I. J. Olawuni, E. G. Fakola & C. A. Obafemi · Current Journal of Applied Science and Technology · 2026

Aims: The aim is to synthesize a range of chemical derivatives and thoroughly evaluate their potential biological activities. This process will involve designing and executing synthetic pathways to obtain the desired compounds, followed by in-depth biological assays to assess pro...

Open access Research Article 10.9734/cjast/2026/v45i94756

Design, Synthesis and Molecular Docking Study Evaluation of Acetylcholinesterase and Butyrylcholinesterase Inhibition Potential of 8-bromo-4-(2-(phenylethylidene)hydrazinyl)tetrazolo[1,5-a]quinoxaline Derivatives

F. O. Taiwo, I. J. Olawuni, O. B. Omoyeni, E. G. Fakola & C. A. Obafemi · Annual Research & Review in Biology · 2026

Aims: The aim of this study was to synthesize 8-bromo-4-(2-(1-phenylethylidene)hydrazinyl)tetrazolo[1,5-a]quinoxaline derivatives and assess their acetylcholinesterase and butyrylcholinesterase inhibitory potential. Methods: The 8-bromo-4-(2-(1-phenylethylidene) hydrazinyl)tetraz...

Open access Research Article 10.9734/arrb/2026/v41i92446

Synthesis of Sulfanoquinoxaline-2,3-Dione Hydrazones Derivatives as a Selective Inhibitor for Acetylcholinesterase and Butyryl Cholinesterase

F. O. Taiwo, C. A. Obafemi, E. M. Obuotor & I. J. Olawuni · Journal of Applied Life Sciences International · 2021

Some Sulfanoquinoxaline-2,3-diones hydrazone derivatives (1-8) were synthesized from the reactions of 2,3-dioxoquinoxaline-6-sulfonohydrazine with seven substituted benzaldehydes and acetophenone. All the synthesized compounds were biologically evaluated against cholinesterase’s...

Open access Research Article 10.9734/jalsi/2021/v24i830252

Synthesis of Some Phenylisoindoline-1,3-Diones and their Acetylcholinesterase and Butyryl Cholinesterase Inhibitory Activities

F. O. Taiwo, C. A. Obafemi, E. M. Obuotor & I. J. Olawuni · Journal of Pharmaceutical Research International · 2021

Aims: To synthesize some phthalimides derivatives and evaluate the compounds for their possible biological properties. Methods: The substituted phenylisoindoline-1,3-dione were synthesized from the reactions of N-phenyl phthalimide with different substituted aromatic aldehyde. Th...

Open access Research Article 10.9734/jpri/2021/v33i51B33539

Design, Synthesis, Reactions and Antibacterial Properties of 2-hydrazinyl-3-methyl-6-nitroquinoxaline Derivatives

F. O. Taiwo, C.A. Obafemi & D.A. Akinpelu · Journal of Advances in Microbiology · 2021

Aims: This aims of this study was to synthesis new quinoxaline-based heterocycles and study its antibacterial properties. Objective: This study was designed to synthesis some 3-methyl-6-nitroquinoxaline-2-one with hydrazine moiety, characterize the synthesized compounds, and stud...

Open access Research Article 10.9734/jamb/2021/v21i1130408

Design, Synthesis and Biological Activities of Some phthalimides Derivatives

F. O. Taiwo, C. A. Obafemi, E. M. Obuotor & I. J. Olawuni · Current Journal of Applied Science and Technology · 2021

Aims: To synthesize some phthalimides derivatives and evaluate the compounds for their possible biological properties. Methods: The substituted phenylisoindoline-1,3-dione were synthesized from the reactions of N-phenyl phthalimide with different substituted aromatic aldehyde. Th...

Open access Research Article 10.9734/cjast/2021/v40i3331563

Design, Synthesis and Antibacterial Activity of some 3,6-Dimethlyquinoxaline-2-Hydrazone Derivatives

F. O. Taiwo, C. A. Obafemi, D. A. Akinpelu & T. O. Iyiola · Journal of Applied Life Sciences International · 2021

Aims: This aims of this study was to continue the effort to synthesis new quinoxaline-based heterocycles and study its antibacterial properties. Objective: This study was designed to reacts 3,6-dimethylquinoxaline-2-hydrazine with some substituted aromatic ketones and study their...

Open access Research Article 10.9734/jalsi/2021/v24i630244