Esther Uyoyooghene Olokede

From Spatial Transcriptomics to Clinic-Ready Diagnostic Panels: A Conceptual Review of Translating Tumor Microenvironment Architecture into Practical Cancer Biomarkers

Esther Uyoyooghene Olokede, Kingsley Ugonna Ugoagwu, Olusegun Timothy God-Giveth, Motunrayo Victoria Adigun, Fortune Itoje Ebiala & Salifu Faisal · International Research Journal of Oncology · 2026

Spatial transcriptomics and related spatially resolved profiling technologies have transformed the characterization of tumor microenvironment architecture, revealing spatial patterns of cellular organization that are tightly linked to cancer behavior. However, despite their biolo...

Open access Research Article 10.9734/irjo/2026/v9i1198

Silent Multiorgan Injury in Sickle Cell Disease: Redefining Mortality Beyond Pain Crises

Daniel Obinna Eke, Obiageri Ihuarulam Okeoma, Leo Tata, Salamah Abimbola Junaid, Williams Temidayo Solomon & Esther Uyoyooghene Olokede · International Journal of Research and Reports in Hematology · 2026

Sickle cell disease (SCD) has typically been seen through the prism of acute vaso-occlusive crises and other clinically noticeable issues that call for medical attention. The mortality rate among people with sickle cell disease (SCD) is still much higher than that of the general...

Open access Research Article 10.9734/ijr2h/2026/v9i2224

Epigenetic Toxicology of Endocrine Disrupting Chemicals: Mechanisms, Transgenerational Effects, and Human Health Implications

Chidinma Lorretta Gab-Obinna, Daniel Obinna Eke, Bassey Atte Inyang, Ameh Uyo Praisegod, Harbor Kelechi Chima & Esther Uyoyooghene Olokede · South Asian Research Journal of Natural Products · 2026

Endocrine-disrupting chemicals (EDCs) are exogenous substances that threaten human and environmental health by interfering with hormonal signalling. A growing body of research indicates that EDCs have long-lasting biological effects through epigenetic modifications, such as DNA m...

Open access Research Article 10.9734/sarjnp/2026/v9i2244